⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654114 | 0.75 | — | — | |
| Water SCHEMBL3997763 | 0.73 | — | — | |
| SCHEMBL11340652 | 0.73 | — | — | |
| SCHEMBL22300 | 0.71 | — | — | |
| SCHEMBL1490142 | 0.71 | — | — | |
| SCHEMBL13354747 | 0.71 | — | — | |
| SCHEMBL13312865 | 0.71 | — | — | |
| SCHEMBL11329665 | 0.71 | — | — | |
| SCHEMBL30132067 | 0.69 | — | — | |
| SCHEMBL30358284 | 0.69 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915423-B2 | Dissolving pantoprazole and sodium hydroxide in 2-propanol, tetrahydrofuran, acetonitrile, methanol, ethanol, water, mixtures of sec-butanol and dichloromethane, or ethyl acetate diluent, crystallizing pantoprazole sodium sesquihydrate, isolating | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2011-03-29 | — | — | US | disclosed |
| US-7507829-B2 | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates | TEVA PHARMACEUTICALS INDUSTRIES, LTD (IL) | 2009-03-24 | — | — | US | disclosed |
| US-20080132707-A1 | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates | TEVA PHARMACEUTICALS USA, INC. FOR BARBADOS. | 2008-06-05 | — | — | US | disclosed |
| US-20040177804-A1 | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2004-09-16 | — | — | US | disclosed |
| EP-0495265-B1 | Acid-labile linker molecules | AKZO NOBEL NV (NL) | 1994-08-03 | — | — | EP | disclosed |
| US-5306809-A | Cancer immune therapy | AKZO N.V. (NL) | 1994-04-26 | — | — | US | disclosed |
| EP-0495265-A1 | Acid-labile linker molecules | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |