Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20752315 | 0.83 | KDM4E (0.53) | KMT2AMGLLPHGDHKDM4ETDP1 | |
| SCHEMBL8283794 | 0.82 | KMT2A (0.43) | KMT2AMGLLPHGDHKDM4ETDP1 | |
| SCHEMBL8335750 | 0.80 | F2 (0.46) | KMT2AMGLLPHGDHKDM4ETDP1 | |
| SCHEMBL8335248 | 0.79 | KMT2A (0.52) | KMT2AKDM4ETDP1CYP1A2ALDH1A1 | |
| SCHEMBL26631959 | 0.77 | KMT2A (0.43) | KMT2APHGDHHTT | |
| SCHEMBL16791189 | 0.77 | CYP1A2 (0.44) | KMT2AMGLLPHGDHTDP1HTR1A | |
| SCHEMBL17383667 | 0.76 | TDP1 (0.38) | KMT2AMGLLPHGDHKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL15538853 | 0.75 | CYP1A2 (0.42) | KMT2AMGLLPHGDHTDP1HTR1A | |
| SCHEMBL4945446 | 0.75 | CYP1A2 (0.42) | MGLLPHGDHKDM4ETDP1HTR1A | |
| SCHEMBL12980332 | 0.75 | TDP1 (0.42) | MGLLPHGDHKDM4ETDP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036869-A2 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-03-14 | — | — | WO | disclosed |