SCHEMBL14769840

SCHEMBL14769840

CC1(C)/C(=C\c2c(O)c(=O)c2=O)N(Cc2ccccc2)c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.46
NPSR1 Q6W5P4 2/20 0.44
ELANE P08246 1/20 0.43
HSD17B10 Q99714 5/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
P2RX1 P51575 1/20 0.42
P2RX3 P56373 1/20 0.42
P2RX4 Q99571 1/20 0.42
P2RX7 Q99572 1/20 0.42
MAPT P10636 4/20 0.42
TP53 P04637 2/20 0.41
GAA P10253 1/20 0.39
SCN9A Q15858 1/20 0.39
USP2 O75604 1/20 0.39
MAPK1 P28482 1/20 0.39
LMNA P02545 1/20 0.38
EP300 Q09472 1/20 0.38
CREBBP Q92793 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14769832 0.86 MAPT (0.48) ALDH1A1NPSR1HSD17B10SMN1; SMN2MAPT
SCHEMBL16319609 0.86 MAPT (0.48) ALDH1A1NPSR1HSD17B10SMN1; SMN2MAPT
SCHEMBL12156970 0.85 MAPT (0.47) ALDH1A1NPSR1HSD17B10SMN1; SMN2MAPT
SCHEMBL15947424 0.84 MAPT (0.47) ALDH1A1NPSR1HSD17B10SMN1; SMN2MAPT
SCHEMBL14773230 0.84 MEN1 (0.41) ALDH1A1NPSR1HSD17B10SMN1; SMN2MAPT
SCHEMBL14769839 0.82 ALDH1A1 (0.47) ALDH1A1NPSR1HSD17B10SMN1; SMN2MAPT
SCHEMBL14769836 0.81 KDM4E (0.39) ALDH1A1NPSR1HSD17B10SMN1; SMN2MAPT
SCHEMBL12156977 0.81 ALDH1A1 (0.43) ALDH1A1NPSR1SMN1; SMN2MAPTSCN9A
SCHEMBL21314807 0.81 ALDH1A1 (0.43) ALDH1A1NPSR1SMN1; SMN2MAPTSCN9A
SCHEMBL21314809 0.81 ALDH1A1 (0.43) ALDH1A1NPSR1SMN1; SMN2MAPTSCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130061929-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR PRODUCING PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-03-14 US disclosed
US-20130061929-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR PRODUCING PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-03-14 US disclosed