Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GYS1 | P13807 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065309 | 0.89 | CACNA1C (0.43) | CACNA1CCYP1A2CYP1A1CYP1B1POLB | |
| SCHEMBL14770536 | 0.86 | CACNA1C (0.45) | CACNA1CCYP1A2CYP1A1CYP1B1POLB | |
| SCHEMBL14770539 | 0.85 | CACNA1C (0.45) | CACNA1CCYP1A2CYP1A1CYP1B1POLB | |
| SCHEMBL14770528 | 0.83 | NPC1 (0.42) | CACNA1CCYP1A2CYP1A1CYP1B1POLB | |
| SCHEMBL14770526 | 0.83 | CACNA1C (0.48) | CACNA1CCYP1A2CYP1A1CYP1B1POLB | |
| SCHEMBL14770531 | 0.81 | CACNA1C (0.40) | CACNA1CCYP1A2CYP1A1CYP1B1POLB | |
| SCHEMBL14770538 | 0.80 | CACNA1C (0.40) | CACNA1CCYP1A2CYP1A1CYP1B1LMNA | |
| SCHEMBL14770527 | 0.78 | CACNA1C (0.38) | CACNA1CCYP1A2CYP1A1CYP1B1POLB | |
| SCHEMBL14770530 | 0.78 | CACNA1C (0.38) | CACNA1CCYP1A2CYP1A1CYP1B1POLB | |
| SCHEMBL14770537 | 0.78 | CACNA1C (0.38) | CACNA1CCYP1A2CYP1A1CYP1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096531-B2 | Fused imidazole derivative | TOA EIYO LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA EIYO LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | CACNA1E, CACNA1G, CACNA1A | CACNA1C 16/4885CYP1A2 2887/4885CYP1A1 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.