Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085867 | 1.00 | HTT (0.64) | HTTTDP1POLBAPEX1TSHR | |
| SCHEMBL25894065 | 0.95 | HTT (0.70) | HTTTDP1POLBAPEX1TSHR | |
| SCHEMBL18503403 | 0.95 | HTT (0.70) | HTTTDP1POLBAPEX1TSHR | |
| SCHEMBL18927175 | 0.93 | HTT (0.68) | HTTTDP1POLBAPEX1TSHR | |
| SCHEMBL28897371 | 0.92 | HTT (0.64) | HTTTDP1POLBAPEX1TSHR | |
| SCHEMBL5332386 | 0.92 | TDP1 (0.52) | HTTTDP1POLBAPEX1PPARA | |
| SCHEMBL5332382 | 0.92 | TDP1 (0.52) | HTTTDP1POLBAPEX1PPARA | |
| SCHEMBL7751294 | 0.90 | HTT (0.67) | HTTTDP1POLBAPEX1TSHR | |
| SCHEMBL29089237 | 0.90 | HTT (0.64) | HTTTDP1POLBAPEX1TSHR | |
| SCHEMBL28729857 | 0.90 | POLB (0.64) | HTTTDP1POLBAPEX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7914485-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100016941-A1 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-7582078-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| EP-2068959-A2 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | Boston Scientific Limited (BB) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008045166-A2 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | BOSTON SCIENTIFIC LIMITED (BB) | 2008-04-17 | — | — | WO | disclosed |
| US-20070191814-A1 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2007-08-16 | — | — | US | disclosed |