Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332382 | 1.00 | TDP1 (0.52) | TDP1POLBAPEX1HTTPPARA | |
| SCHEMBL20828630 | 0.94 | POLB (0.57) | TDP1POLBAPEX1HTTPPARA | |
| SCHEMBL1477075 | 0.92 | HTT (0.64) | TDP1POLBAPEX1HTTPPARA | |
| SCHEMBL18085867 | 0.92 | HTT (0.64) | TDP1POLBAPEX1HTTPPARA | |
| SCHEMBL24565142 | 0.91 | POLB (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL20828629 | 0.89 | POLB (0.52) | TDP1POLBAPEX1HTTPPARA | |
| SCHEMBL4455307 | 0.89 | POLB (0.56) | TDP1POLBAPEX1HTTPPARA | |
| SCHEMBL2785663 | 0.89 | POLB (0.56) | TDP1POLBAPEX1HTTPPARA | |
| SCHEMBL14597118 | 0.88 | NPC1 (0.55) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL12563532 | 0.87 | MAPT (0.44) | TDP1POLBAPEX1HTTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007131707-A | AZO FUNCTIONAL GROUP-CONTAINING COPOLYMER | NITTO DENKO CORP | 2007-05-31 | — | — | JP | disclosed |