Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017282 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL5114077 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL1037842 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL14620877 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL6426932 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL165540 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL24912524 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL1037843 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL22540086 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A | |
| SCHEMBL12440357 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CCR5HTR2CHTR6HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5585 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4213843-B1 | MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-05-06 | — | — | EP | claimed |
| US-20250188057-A1 | NON-AROMATIC CYCLIC-PYRIMIDINE ANALOGS AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-06-12 | — | — | US | claimed |
| CN-111655695-B | Substituted furopyrimidine compounds as PDE1 inhibitors | 达特神经科学有限公司 | 2025-05-27 | — | — | CN | claimed |
| WO-2025076059-A1 | ROCAGLATE DERIVATIVES AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-04-10 | — | — | WO | claimed |
| EP-4490148-A2 | NON-AROMATIC CYCLIC-PYRIMIDINE ANALOGS AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | Merck Sharp & Dohme LLC (US) | 2025-01-15 | — | — | EP | claimed |
| EP-3792256-B1 | PYRIDINE COMPOUNDS AS PI3K-GAMMA INHIBITORS | INCYTE CORP (US) | 2024-10-23 | — | — | EP | claimed |
| US-12108762-B2 | Methods of controlling crop pests using aromatic amide insect repellents, methods of making aromatic amide insect repellents, and novel aromatic amide insect repellents | MAITRA SANTANU (US) | 2024-10-08 | — | — | US | claimed |
| US-20240092815-A1 | ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-03-21 | — | — | US | claimed |
| US-20240018140-A1 | MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-01-18 | — | — | US | claimed |
| CN-117377675-A | Bruton's tyrosine kinase degradation agent containing parallel ring or spiro ring | 正大天晴药业集团股份有限公司 | 2024-01-09 | — | — | CN | claimed |
| EP-0185792-A1 | Process for production of decahydroisoquinoline | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1986-07-02 | — | — | EP | claimed |
| EP-0158927-A2 | Process for the treatment of heart failure | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-23 | — | — | EP | claimed |
| EP-0158157-A1 | Method for the treatment of glaucoma | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-16 | — | — | EP | claimed |
| US-4525301-A | REACTING TRIFLUOROMETHANE SULFONIC ACID DERIVATIVES WITH AMINO ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-25 | — | — | US | claimed |
| EP-0135182-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | claimed |
| EP-0135181-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | claimed |
| EP-0126986-A1 | Process for producing N-alkylated dipeptides and their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-05 | — | — | EP | claimed |
| US-4404206-A | HYPOTENSIVE AND CARDIOTONIC AGENTS | SCIENCE UNION ET CIE (FR) | 1983-09-13 | — | — | US | claimed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | claimed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | claimed |