SCHEMBL1477522

SCHEMBL1477522

NS(=O)(=O)c1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.73
ALDH1A1 P00352 7/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
ADORA2A P29274 2/20 0.57
MAPT P10636 6/20 0.50
MAPK1 P28482 6/20 0.50
L3MBTL1 Q9Y468 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
TDP1 Q9NUW8 4/20 0.50
LMNA P02545 3/20 0.50
MCL1 Q07820 2/20 0.50
POLB P06746 1/20 0.50
THRB P10828 1/20 0.50
PKM P14618 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
MAOA P21397 6/20 0.48
CYP3A4 P08684 2/20 0.48
MAOB P27338 2/20 0.48
HPGD P15428 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10775549 0.94 STAT3 (0.81) STAT3ALDH1A1SMN1; SMN2ADORA2AMAPT
SCHEMBL10778903 0.92 STAT3 (0.72) STAT3ALDH1A1SMN1; SMN2ADORA2AMAPT
SCHEMBL8266360 0.87 STAT3 (0.57) STAT3ALDH1A1SMN1; SMN2ADORA2AMAPT
SCHEMBL29382217 0.85 STAT3 (1.00) STAT3ALDH1A1SMN1; SMN2MAPTMAPK1
SCHEMBL22606378 0.85 STAT3 (0.69) STAT3ALDH1A1SMN1; SMN2ADORA2AMAPK1
SCHEMBL12310760 0.85 STAT3 (1.00) STAT3ALDH1A1SMN1; SMN2MAPTMAPK1
SCHEMBL31231857 0.85 STAT3 (1.00) STAT3ALDH1A1SMN1; SMN2MAPTMAPK1
SCHEMBL1346951 0.83 ALDH1A1 (0.65) STAT3ALDH1A1SMN1; SMN2ADORA2AMAPT
SCHEMBL27944611 0.82 STAT3 (0.55) STAT3ALDH1A1SMN1; SMN2CA1CA2
SCHEMBL230644 0.80 ALDH1A1 (0.61) STAT3ALDH1A1SMN1; SMN2ADORA2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777122-B2 Thickening compositions, and related materials and processes GENERAL ELECTRIC COMPANY (US) 2017-10-03 US claimed
US-20160297934-A1 THICKENING COMPOSITIONS, AND RELATED MATERIALS AND PROCESSES U.S. DEPARTMENT OF ENERGY 2016-10-13 US claimed
WO-2016164691-A1 THICKENING COMPOSITIONS, AND RELATED MATERIALS AND PROCESSES GENERAL ELECTRIC COMPANY (US) 2016-10-13 WO claimed
EP-0008641-B1 ANTHRAQUINONESULPHONAMIDES AND PROCESS FOR THEIR MANUFACTURE CIBA-GEIGY AG (CH) 1982-01-13 EP claimed
US-4276224-A Anthraquinone sulphonamide compounds and preparation CIBA-GEIGY CORPORATION (US) 1981-06-30 US claimed
EP-0024746-A1 Process for the absorption and removal of hydrogen sulphide as elemental sulphur from gases or gas mixtures, and an alkaline solution containing a derivative of anthraquinone sulfonic acid amide CIBA-GEIGY AG (CH) 1981-03-11 EP claimed
US-4251493-A DESULFURIZATION USING ANTHRAQUINONE SULFONAMIDE AND COMPOUND OF POLYVALENT METAL CIBA-GEIGY CORPORATION (US) 1981-02-17 US claimed
EP-0008641-A1 Anthraquinonesulphonamides and process for their manufacture CIBA-GEIGY AG (CH) 1980-03-19 EP claimed
US-9777122-B2 Thickening compositions, and related materials and processes GENERAL ELECTRIC COMPANY (US) 2017-10-03 US disclosed
US-9777122-B2 Thickening compositions, and related materials and processes GENERAL ELECTRIC COMPANY (US) 2017-10-03 US disclosed
CN-106147284-A A kind of synthesis technique of paratonere 202 高邮市助剂厂 2016-11-23 CN disclosed
US-20160297934-A1 THICKENING COMPOSITIONS, AND RELATED MATERIALS AND PROCESSES U.S. DEPARTMENT OF ENERGY 2016-10-13 US disclosed
WO-2016164691-A1 THICKENING COMPOSITIONS, AND RELATED MATERIALS AND PROCESSES GENERAL ELECTRIC COMPANY (US) 2016-10-13 WO disclosed
WO-2016164691-A1 THICKENING COMPOSITIONS, AND RELATED MATERIALS AND PROCESSES GENERAL ELECTRIC COMPANY (US) 2016-10-13 WO disclosed
US-4251492-A REMOVAL OF HYDROGEN SULFIDE FROM GASES OR LIQUID HYDROCARBONS USING A PHOSPHONIC ACID COMPOUND SEQUESTERING AGENT CIBA-GEIGY CORPORATION (US) 1981-02-17 US disclosed
US-4251493-A DESULFURIZATION USING ANTHRAQUINONE SULFONAMIDE AND COMPOUND OF POLYVALENT METAL CIBA-GEIGY CORPORATION (US) 1981-02-17 US disclosed
EP-0008640-A1 Method for the removal of hydrogen sulfide from gases or liquid hydrocarbons and gases or liquid hydrocarbons thus purified CIBA-GEIGY AG (CH) 1980-03-19 EP disclosed
EP-0008641-A1 Anthraquinonesulphonamides and process for their manufacture CIBA-GEIGY AG (CH) 1980-03-19 EP disclosed
EP-0008641-A1 Anthraquinonesulphonamides and process for their manufacture CIBA-GEIGY AG (CH) 1980-03-19 EP disclosed
EP-0008641-A1 Anthraquinonesulphonamides and process for their manufacture CIBA-GEIGY AG (CH) 1980-03-19 EP disclosed