Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7191701 | 0.84 | NPC1 (0.38) | NPC1RAB9APNMTCYP2C19 | |
| Hydrochloric Acid SCHEMBL22261430 | 0.83 | NPC1 (0.53) | NPC1RAB9APNMTALDH1A1HTR2B | |
| SCHEMBL4469957 | 0.80 | NPC1 (0.45) | NPC1RAB9APNMTALDH1A1HTR2B | |
| Hydrochloric Acid SCHEMBL7634665 | 0.79 | NPC1 (0.44) | NPC1RAB9APNMTALDH1A1HTR2B | |
| Hydrochloric Acid SCHEMBL6302943 | 0.79 | NPC1 (0.44) | NPC1RAB9APNMTALDH1A1HTR2B | |
| Hydrochloric Acid SCHEMBL674547 | 0.79 | NPC1 (0.38) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL673104 | 0.79 | NPC1 (0.38) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL675284 | 0.79 | NPC1 (0.38) | NPC1RAB9A | |
| SCHEMBL17644783 | 0.78 | NPC1 (0.40) | NPC1RAB9APNMTALDH1A1HTR2B | |
| Hydrochloric Acid SCHEMBL17644781 | 0.77 | NPC1 (0.40) | NPC1RAB9APNMTALDH1A1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570472-A1 | LUBRICATING OIL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2013-03-20 | — | — | EP | disclosed |