Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7634665 | 0.99 | NPC1 (0.44) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL6302943 | 0.99 | NPC1 (0.44) | NPC1RAB9APNMTHTR2BHTR7 | |
| Butane SCHEMBL7921892 | 0.95 | NPC1 (0.41) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL7040232 | 0.92 | RAB9A (0.39) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL8065202 | 0.87 | NPC1 (0.41) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL1081333 | 0.86 | NPC1 (0.39) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL6908139 | 0.85 | NPC1 (0.39) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL22261430 | 0.84 | NPC1 (0.53) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL2807931 | 0.83 | NPC1 (0.37) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL16239749 | 0.83 | NPC1 (0.37) | NPC1RAB9APNMTHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393851-A | Coordination catalyst for polymerization of alpha-olefins | FINA TECHNOLOGY, INC. (US) | 1995-02-28 | — | — | US | claimed |
| EP-0945471-B1 | CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS | IDEMITSU KOSAN CO (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-6713574-B2 | POLYMERIZING ETHYLENE, ALPHA-OLEFIN AND DIENE WITH A ZIRCONIUM METALLOCENE CATALYST HAVING AN UNSUBSTITUTED CYCLOPENTADIENYL LIGAND, A MULTIPLY SUBSTITUTED CYCLOPENTADIENYL LIGAND, THAT ARE BRIDGED WITH A GROUP 14 ELEMENT | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-03-30 | — | — | US | disclosed |
| EP-0974601-B1 | Olefin polymerization catalyst and process for producing olefin polymer | JAPAN POLYCHEM CORP (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6486278-B1 | Ethylene copolymerization process | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-11-26 | — | — | US | disclosed |
| US-6444763-B1 | Polymerization of olefins | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-09-03 | — | — | US | disclosed |
| EP-0874006-B1 | Phyllosilicate-supported catalyst for the polymerisation of olefins | MITSUBISHI CHEM CORP (JP) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000069959-A2 | POLYMER LAYERED INORGANIC NANOCOMPOSITES | NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY (US) | 2000-11-23 | — | — | WO | disclosed |
| US-6048817-A | Polymerization of olefins | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0974601-A2 | Olefin polymerization catalyst and process for producing olefin polymer | Japan Polychem Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |
| EP-0874006-A1 | Polymerisation of olefins | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0839842-A2 | Ethylene-alpha-olefin copolymer | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-05-06 | — | — | EP | disclosed |
| EP-0399347-B1 | Process for preparing a Syndio-isoblockpolymer | HOECHST AG (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5308811-A | Catalyst for polymerizing an olefin and method for producing an olefin polymer | MITSUBISHI KASEI CORPORATION (JP) | 1994-05-03 | — | — | US | disclosed |