Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 18/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069513 | 0.92 | GHSR (0.46) | GHSR | |
| SCHEMBL3068014 | 0.90 | GHSR (0.48) | GHSR | |
| SCHEMBL3069713 | 0.88 | GHSR (0.52) | GHSR | |
| SCHEMBL3072628 | 0.87 | GHSR (0.51) | GHSR | |
| SCHEMBL3077085 | 0.87 | GHSR (0.44) | GHSR | |
| SCHEMBL3062808 | 0.87 | GHSR (0.46) | GHSR | |
| SCHEMBL3080121 | 0.87 | GHSR (0.47) | GHSR | |
| SCHEMBL3067819 | 0.86 | GHSR (0.48) | GHSR | |
| SCHEMBL3067390 | 0.86 | GHSR (0.52) | GHSR | |
| SCHEMBL3072735 | 0.85 | GHSR (0.45) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951675-B1 | TETRAHYDROISOQUINOLINE AS LXR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2013-03-20 | — | — | EP | disclosed |