Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 14/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3066451 | 0.94 | GHSR (0.47) | GHSRPOLB | |
| SCHEMBL3067883 | 0.92 | GHSR (0.45) | GHSRPOLB | |
| SCHEMBL3067978 | 0.92 | GHSR (0.45) | GHSRPOLB | |
| SCHEMBL3074278 | 0.91 | GHSR (0.45) | GHSRACACB | |
| SCHEMBL3074667 | 0.91 | GHSR (0.45) | GHSRACACB | |
| SCHEMBL3066771 | 0.91 | GHSR (0.50) | GHSR | |
| SCHEMBL3077111 | 0.89 | GHSR (0.43) | GHSRACACB | |
| SCHEMBL3074287 | 0.88 | GHSR (0.43) | GHSR | |
| SCHEMBL3069115 | 0.88 | GHSR (0.47) | GHSRPOLB | |
| SCHEMBL3081269 | 0.88 | GHSR (0.47) | GHSRPOLBACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951675-B1 | TETRAHYDROISOQUINOLINE AS LXR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2013-03-20 | — | — | EP | disclosed |