Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AIMP2 | Q13155 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775689 | 0.95 | NPC1 (0.44) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL14775709 | 0.86 | PTGS1 (0.41) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL27347661 | 0.81 | CYP19A1 (0.41) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL3666847 | 0.79 | NPC1 (0.49) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL1207688 | 0.79 | NPC1 (0.49) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL3733123 | 0.79 | NPC1 (0.49) | CYP19A1NPC1RAB9AAIMP2MAPT | |
| SCHEMBL9800594 | 0.76 | HTT (0.50) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL5169684 | 0.76 | HTT (0.50) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL5172603 | 0.76 | HTT (0.50) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL1208766 | 0.73 | NPC1 (0.55) | CYP19A1NPC1RAB9AAIMP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240467-B1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | EVOTEC AG (DE) | 2013-03-20 | — | — | EP | claimed |