Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775665 | 0.86 | CYP19A1 (0.42) | FFAR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL14775689 | 0.81 | NPC1 (0.44) | FFAR1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL909079 | 0.79 | GAA (0.44) | PTGS1PTGS2FFAR1KDM4EALDH1A1 | |
| SCHEMBL909078 | 0.79 | GAA (0.44) | PTGS1PTGS2FFAR1KDM4EALDH1A1 | |
| SCHEMBL909917 | 0.79 | GAA (0.44) | PTGS1PTGS2FFAR1KDM4EALDH1A1 | |
| SCHEMBL7446942 | 0.77 | GAA (0.45) | PTGS1PTGS2FFAR1ALDH1A1HPGD | |
| SCHEMBL9800594 | 0.76 | HTT (0.50) | ALDH1A1HPGDHSD17B10CYP2C19KMT2A | |
| SCHEMBL5172603 | 0.76 | HTT (0.50) | ALDH1A1HPGDHSD17B10CYP2C19KMT2A | |
| SCHEMBL5169684 | 0.76 | HTT (0.50) | ALDH1A1HPGDHSD17B10CYP2C19KMT2A | |
| SCHEMBL909704 | 0.73 | PTGS1 (0.47) | PTGS1PTGS2FFAR1HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240467-B1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | EVOTEC AG (DE) | 2013-03-20 | — | — | EP | claimed |