Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 7/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18783656 | 0.91 | CCR5 (0.59) | PTGER1SLC6A4CCR5STAT3MRGPRX4 | |
| SCHEMBL14774727 | 0.88 | STAT3 (0.46) | PTGER1SMN1; SMN2ALDH1A1LMNASLC6A4 | |
| SCHEMBL14774657 | 0.87 | SMN1; SMN2 (0.49) | PTGER1SMN1; SMN2ALDH1A1LMNASLC6A4 | |
| SCHEMBL562155 | 0.84 | PTGER1 (0.55) | PTGER1SLC6A4CCR5STAT3 | |
| SCHEMBL14774575 | 0.84 | SLC6A4 (0.56) | PTGER1SLC6A4CCR5STAT3MRGPRX4 | |
| SCHEMBL14774767 | 0.84 | CCR5 (0.47) | PTGER1SMN1; SMN2ALDH1A1LMNASLC6A4 | |
| SCHEMBL14774744 | 0.84 | MEN1 (0.48) | PTGER1SMN1; SMN2LMNASLC6A4MEN1 | |
| SCHEMBL14774604 | 0.83 | MEN1 (0.62) | PTGER1SMN1; SMN2ALDH1A1CCR5STAT3 | |
| SCHEMBL30866179 | 0.83 | MEN1 (0.62) | PTGER1SMN1; SMN2ALDH1A1CCR5STAT3 | |
| SCHEMBL14774605 | 0.82 | PTGER1 (0.46) | PTGER1SMN1; SMN2ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766344-B1 | EP1 RECEPTOR LIGANDS | ESTEVE LABOR DR (ES) | 2017-05-03 | — | — | EP | disclosed |
| EP-2570125-A1 | Ep1 receptor ligands | Almirall, S.A. (ES) | 2013-03-20 | — | — | EP | disclosed |