SCHEMBL14775927

SCHEMBL14775927

CCCCCCCCCCCNc1ncnc(N(CCCC)C2CC(C)(C)NC(C)(C)C2)n1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DNM2 P50570 11/20 0.38
MERTK Q12866 6/20 0.33
FLT3 P36888 4/20 0.33
TYRO3 Q06418 4/20 0.33
GAS6 Q14393 4/20 0.33
S1PR2 O95136 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
AXL P30530 1/20 0.31
KCNH3 Q9ULD8 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11079434 0.89 DNM2 (0.31) DNM2
SCHEMBL13415272 0.88 DNM2 (0.36) DNM2KCNH3KMT2A
SCHEMBL13415271 0.88 DNM2 (0.36) DNM2KCNH3KMT2A
SCHEMBL3133092 0.88 DNM2 (0.36) DNM2KCNH3KMT2A
SCHEMBL9367814 0.87 DNM2 (0.34) DNM2KCNH3KMT2A
SCHEMBL13415269 0.85 DNM2 (0.36) DNM2KCNH3KMT2A
SCHEMBL3145900 0.85 DNM2 (0.36) DNM2KCNH3KMT2A
SCHEMBL11076632 0.85 CHRM1 (0.32)
SCHEMBL28859104 0.85 HTT (0.31) SMN1; SMN2
SCHEMBL11086940 0.85 IGF1R (0.32) DNM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2204420-B1 SYNTHETIC RESIN COMPOSITION AND AUTOMOTIVE INTERIOR/EXTERIOR MATERIAL ADEKA CORP (JP) 2013-03-20 EP disclosed