Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775884 | 0.92 | HDAC1 (0.65) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775765 | 0.87 | KCNH2 (0.64) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775987 | 0.87 | HDAC1 (0.63) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775970 | 0.86 | HDAC1 (0.62) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775855 | 0.85 | HDAC1 (0.61) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775896 | 0.85 | HDAC1 (0.70) | HDAC1HDAC2 | |
| SCHEMBL2692243 | 0.83 | HDAC1 (0.70) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775595 | 0.83 | HDAC1 (0.59) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775684 | 0.83 | HDAC1 (0.57) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14775767 | 0.83 | HDAC1 (0.58) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991226-B1 | INHIBITORS OF HISTONE DEACETYLASE | MERCK SHARP & DOHME (US) | 2013-03-20 | — | — | EP | claimed |