Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.34 |
| ▸ | FDPS | P14324 | 9/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269092 | 0.85 | TSHR (0.44) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL29067135 | 0.81 | SPHK2 (0.31) | — | |
| SCHEMBL6079698 | 0.77 | — | — | |
| SCHEMBL7269333 | 0.75 | — | — | |
| SCHEMBL5964919 | 0.74 | TSHR (0.38) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL27144573 | 0.74 | SMN1; SMN2 (0.38) | TSHRGGPS1FDPSCES2 | |
| SCHEMBL28214778 | 0.74 | TSHR (0.38) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL13517253 | 0.74 | SPHK2 (0.37) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL2234723 | 0.73 | TSHR (0.36) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL17529654 | 0.73 | TSHR (0.36) | TSHRTHRBGGPS1FDPSCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072648-A1 | SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |