Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.39 |
| ▸ | FDPS | P14324 | 9/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778162 | 0.85 | TSHR (0.36) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL27144573 | 0.82 | SMN1; SMN2 (0.38) | TSHRGGPS1FDPSCES2LPAR1 | |
| SCHEMBL13517253 | 0.82 | SPHK2 (0.37) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL13517700 | 0.80 | OPRM1 (0.32) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL15062356 | 0.80 | OPRM1 (0.32) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL638853 | 0.79 | OPRM1 (0.44) | TSHRTHRBGGPS1FDPSDNM1 | |
| SCHEMBL13518776 | 0.79 | SPHK2 (0.35) | — | |
| SCHEMBL28438544 | 0.78 | TSHR (0.32) | TSHRTHRBFDPS | |
| SCHEMBL3048556 | 0.78 | TSHR (0.44) | TSHRTHRBGGPS1FDPSDNM1 | |
| Isopropyl Alcohol SCHEMBL5323118 | 0.77 | GGPS1 (0.40) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8281592-B2 | Direct contact heat exchanger and methods for making and using same | KALINA POWER LTD. (AU) | 2012-10-09 | — | — | US | disclosed |
| US-20110024084-A1 | DIRECT CONTACT HEAT EXCHANGER AND METHODS FOR MAKING AND USING SAME | KALEX, LLC (US) | 2011-02-03 | — | — | US | disclosed |
| WO-2011014764-A2 | A DIRECT CONTACT HEAT EXCHANGER AND METHODS FOR MAKING AND USING SAME | KALEX, LLC (US) | 2011-02-03 | — | — | WO | disclosed |