Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14780534 | 0.72 | GAA (0.32) | GAAHPGD | |
| SCHEMBL578630 | 0.64 | CTNNB1 (0.31) | — | |
| SCHEMBL14783410 | 0.64 | CTNNB1 (0.37) | — | |
| SCHEMBL13459862 | 0.63 | NPC1 (0.34) | — | |
| SCHEMBL2768694 | 0.61 | — | — | |
| SCHEMBL30565540 | 0.58 | SHMT2 (0.40) | GAAHPGD | |
| SCHEMBL910405 | 0.57 | — | — | |
| SCHEMBL5016661 | 0.57 | — | — | |
| SCHEMBL2767829 | 0.56 | GAA (0.51) | NOTUMGAAHPGD | |
| SCHEMBL621556 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013038374-A1 | PROCESS FOR MANUFACTURING A SYNTHETIC INTERMEDIATE | ACTELION PHARMACEUTICALS LTD (CH) | 2013-03-21 | — | — | WO | disclosed |
| WO-2013038374-A1 | PROCESS FOR MANUFACTURING A SYNTHETIC INTERMEDIATE | ACTELION PHARMACEUTICALS LTD (CH) | 2013-03-21 | — | — | WO | disclosed |