Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4800217 | 0.89 | SIRT5 (0.55) | GRIA2HSD17B10ALOX15USP2ADORA3 | |
| SCHEMBL4800520 | 0.89 | SLC7A5 (0.47) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL4800230 | 0.89 | SIRT5 (0.55) | GRIA2HSD17B10ALOX15USP2ADORA3 | |
| SCHEMBL4800531 | 0.89 | SLC7A5 (0.47) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL31369759 | 0.87 | GRIA2 (0.59) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL2121998 | 0.85 | SLC7A5 (0.55) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL2122000 | 0.85 | SLC7A5 (0.55) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL31083609 | 0.85 | SLC7A5 (0.55) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL3309849 | 0.85 | GRB2 (0.44) | SLC7A5PTGS1PKMALPIXIAP | |
| SCHEMBL3309854 | 0.85 | GRB2 (0.44) | SLC7A5PTGS1PKMALPIXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399614-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-03-19 | — | — | US | disclosed |