SCHEMBL14780804

SCHEMBL14780804

FC(F)(CI)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24421395 0.90
SCHEMBL30095923 0.81
SCHEMBL4337634 0.78 LMNA (0.38) LMNA
SCHEMBL20848204 0.78 LMNA (0.38) LMNA
SCHEMBL4337670 0.78 LMNA (0.38) LMNA
SCHEMBL810559 0.78 LMNA (0.38) LMNA
SCHEMBL419390 0.78
SCHEMBL30194018 0.78 LMNA (0.31) LMNA
SCHEMBL7638924 0.78 LMNA (0.42) LMNA
SCHEMBL30095971 0.78 LMNA (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399684-B2 Sulfonamide-based organocatalysts and method for their use STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) 2013-03-19 US disclosed