Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029909 | 0.87 | HPGD (0.38) | HPGDGAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14029805 | 0.77 | POLB (0.43) | HPGDGAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5002702 | 0.77 | TDP1 (0.43) | HPGDGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14029900 | 0.76 | HSP90AB1 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL4999280 | 0.73 | HPGD (0.49) | HPGDGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5002786 | 0.72 | HSP90AA1 (0.44) | HPGDGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14924954 | 0.71 | POLB (0.42) | HPGDGAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5002796 | 0.71 | ADAM17 (0.47) | HPGDGAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14029905 | 0.71 | KMT2A (0.41) | HPGDGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5006434 | 0.70 | CHRNE (0.52) | HPGDGAAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399464-B2 | using a triazole compound; anticancer agent | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-19 | — | — | US | disclosed |