Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 10/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27888086 | 0.81 | CYP1A2 (0.57) | KDM4EL3MBTL1KMOALDH1A1CYP1A2 | |
| SCHEMBL17674527 | 0.81 | HPGDS (0.41) | KMO | |
| SCHEMBL87765 | 0.81 | KDM4E (0.55) | KDM4EKDM3AKDM6BKDM5CKDM4C | |
| SCHEMBL31126262 | 0.81 | KDM4E (0.55) | KDM4EKDM3AKDM6BKDM5CKDM4C | |
| Hydrochloric Acid SCHEMBL21173938 | 0.79 | KDM4E (0.53) | KDM4EKDM3AKDM6BKDM5CKDM4C | |
| Bromide SCHEMBL21331919 | 0.79 | KDM4E (0.53) | KDM4EKDM3AKDM6BKDM5CKDM4C | |
| Fluoride SCHEMBL21332111 | 0.79 | KDM4E (0.53) | KDM4EKDM3AKDM6BKDM5CKDM4C | |
| SCHEMBL164625 | 0.78 | MAPK1 (0.46) | KDM4EKDM3AKDM6BKDM5CKDM4C | |
| SCHEMBL4384494 | 0.78 | MAPK1 (0.46) | KDM4EKDM3AKDM6BKDM5CKDM4C | |
| SCHEMBL15500861 | 0.76 | MAPT (0.46) | KDM4EKDM3AKDM6BKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755942-A2 | THERAPEUTIC COMPOUNDS | Arizona Board of Regents, a Body Corporate of the State of Arizona acting for and on behalf of Arizona State University (US) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013040227-A2 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2013-03-21 | — | — | WO | disclosed |