Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexachlorobutadiene SCHEMBL80889 | 1.00 | TSHR (0.50) | TSHR | |
| Hexachlorobutadiene SCHEMBL8871886 | 1.00 | TSHR (0.50) | TSHR | |
| SCHEMBL8581113 | 0.94 | TSHR (0.44) | TSHR | |
| Hexachlorobutadiene SCHEMBL2314562 | 0.84 | TSHR (0.36) | TSHR | |
| Lindane SCHEMBL6241025 | 0.80 | LMNA (0.46) | TSHR | |
| Perchlorobenzene SCHEMBL5859427 | 0.80 | TSHR (0.40) | TSHR | |
| SCHEMBL6152327 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL11007369 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL22931362 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL28726760 | 0.76 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2756304-A1 | MEANS AND METHODS FOR ASSESSING KIDNEY TOXICITY | BASF SE (DE) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013038369-A1 | MEANS AND METHODS FOR ASSESSING KIDNEY TOXICITY | BASF SE (DE) | 2013-03-21 | — | — | WO | disclosed |