Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL14784307 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28420909 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL1332143 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2351948 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL2275798 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL852 | 0.94 | — | — | |
| Bicarbonate SCHEMBL23246204 | 0.88 | — | — | |
| Bicarbonate SCHEMBL1603055 | 0.88 | — | — | |
| Bicarbonate SCHEMBL2256461 | 0.88 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL9053906 | 0.88 | CA4 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673139-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| EP-4628163-A1 | NOVEL HETEROARYL AMINOPROPANOL DERIVATIVES | Novartis AG (CH) | 2025-10-08 | — | — | EP | disclosed |
| EP-4323062-B1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | NOVARTIS AG (CH) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024182742-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| US-20240199593-A1 | Novel Heteroaryl Aminopropanol Derivatives | NOVARTIS PHARMA AG (CH) | 2024-06-20 | — | — | US | disclosed |
| US-11932630-B2 | Heteroaryl aminopropanol derivatives | NOVARTIS AG (CH) | 2024-03-19 | — | — | US | disclosed |
| EP-4323062-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | Novartis AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| WO-2023165551-A1 | SIX-MEMBERED AROMATIC RING-PYRROLIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-09-07 | — | — | WO | disclosed |
| EP-3814332-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-20220348566-A1 | Novel Heteroaryl Aminopropanol Derivatives | NOVARTIS AG (CH) | 2022-11-03 | — | — | US | disclosed |
| WO-2022219546-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | NOVARTIS AG (CH) | 2022-10-20 | — | — | WO | disclosed |
| EP-3814332-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-05 | — | — | EP | disclosed |
| WO-2020002563-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-02 | — | — | WO | disclosed |
| WO-2014001121-A1 | ISOTHIAZOLE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-03 | — | — | WO | disclosed |
| WO-2013036994-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-03-21 | — | — | WO | disclosed |