Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411991 | 0.92 | MAOB (0.67) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL339813 | 0.89 | LMNA (0.82) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL14786200 | 0.87 | MAOB (0.71) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL15583709 | 0.85 | MAOB (0.59) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL18284416 | 0.85 | MAOB (0.59) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL29120768 | 0.85 | MAOB (0.54) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL10609652 | 0.84 | LMNA (0.75) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL24975216 | 0.84 | MAOB (0.57) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL20416496 | 0.84 | LMNA (0.58) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL3572357 | 0.84 | MAOB (0.57) | MAOBLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |
| WO-2013037404-A1 | PHOTOREFRACTIVE COMPOSITE | Westfälische Wilhelms Universität Münster (DE) | 2013-03-21 | — | — | WO | disclosed |