Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 15/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570023 | 0.88 | EPHX2 (0.49) | POLBEPHX2EPHX1ALDH1A1FAAH | |
| SCHEMBL14793970 | 0.87 | EPHX2 (0.49) | POLBEPHX2MAPTEPHX1ALDH1A1 | |
| SCHEMBL2568013 | 0.85 | EPHX2 (0.52) | POLBEPHX2MAPTALDH1A1LMNA | |
| SCHEMBL2571169 | 0.82 | EPHX2 (0.52) | POLBEPHX2MAPTLMNANPC1 | |
| SCHEMBL13197862 | 0.81 | MCHR1 (0.45) | POLBEPHX2MAPTEPHX1FAAH | |
| SCHEMBL1594683 | 0.81 | EPHX2 (0.50) | POLBEPHX2EPHX1ALDH1A1FAAH | |
| SCHEMBL2571142 | 0.79 | EPHX2 (0.54) | POLBEPHX2MAPTALDH1A1FAAH | |
| SCHEMBL2568709 | 0.77 | MEN1 (0.37) | POLBMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13197817 | 0.77 | EPHX2 (0.44) | EPHX2EPHX1ALDH1A1 | |
| SCHEMBL2569969 | 0.76 | MCHR1 (0.44) | POLBEPHX2MAPTEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755964-B1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS ANTI INFECTIVE CURES GMBH (DE) | 2016-06-22 | — | — | EP | disclosed |
| EP-2755964-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AiCuris GmbH & Co. KG (DE) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013037812-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2013-03-21 | — | — | WO | disclosed |