Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570520 | 0.90 | MEN1 (0.39) | MEN1KMT2ATP53LMNAPOLB | |
| SCHEMBL1594765 | 0.87 | TP53 (0.40) | MEN1KMT2ATP53LMNAPOLB | |
| SCHEMBL1594449 | 0.81 | MEN1 (0.41) | MEN1KMT2ATP53LMNAPOLB | |
| SCHEMBL13197780 | 0.81 | CHRM1 (0.36) | MEN1KMT2ATP53LMNAALDH1A1 | |
| SCHEMBL14786459 | 0.77 | POLB (0.46) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2568640 | 0.76 | MAPT (0.39) | MEN1KMT2ATP53LMNAPOLB | |
| SCHEMBL2572026 | 0.75 | P2RX7 (0.48) | KMT2ATP53LMNAPOLBMAPT | |
| SCHEMBL12706245 | 0.74 | LMNA (0.39) | MEN1KMT2ATP53LMNAPOLB | |
| SCHEMBL2569125 | 0.74 | MAPT (0.39) | MEN1KMT2ATP53POLBALDH1A1 | |
| SCHEMBL2572466 | 0.73 | MAPK1 (0.37) | MEN1KMT2ATP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732901-B1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | AICURIS GMBH & CO KG (DE) | 2011-11-02 | — | — | EP | disclosed |
| EP-1853582-B1 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO KG (DE) | 2009-10-21 | — | — | EP | disclosed |
| EP-1853582-A2 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AiCuris GmbH & Co. KG (DE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1732901-A1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | Bayer HealthCare AG (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2006089664-A2 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2006-08-31 | — | — | WO | disclosed |
| WO-2005092865-A1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | BAYER HEALTHCARE AG (DE) | 2005-10-06 | — | — | WO | disclosed |