⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29006787 | 0.73 | — | — | |
| SCHEMBL8516135 | 0.72 | — | — | |
| SCHEMBL8112919 | 0.70 | — | — | |
| SCHEMBL313208 | 0.70 | — | — | |
| SCHEMBL14127604 | 0.70 | — | — | |
| SCHEMBL43584 | 0.67 | — | — | |
| SCHEMBL10933839 | 0.67 | — | — | |
| SCHEMBL5439701 | 0.67 | — | — | |
| SCHEMBL43918 | 0.67 | — | — | |
| SCHEMBL21828481 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837818-B | It can be used as the acid amides of pyridine 2 of CB2 activators | 霍夫曼-拉罗奇有限公司 | 2017-07-14 | — | — | CN | claimed |
| CN-102596957-B | Substituted pyrazolo [1,5-a ] pyrimidine compounds as TRK kinase inhibitors | 阵列生物制药公司 | 2016-06-29 | — | — | CN | claimed |
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | claimed |
| CN-111377856-B | R-type pyridyloxy carboxylic acid and salt and ester derivatives thereof, preparation method, herbicidal composition and application | 青岛清原化合物有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-108026067-B | 6-amino-quinoline-3-carbonitriles as COT modulators | 吉利德科学公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-110461964-A | Cured film is formed with composition, orientation material and phase difference material | NISSAN CHEMICAL CORP | 2019-11-15 | — | — | CN | disclosed |
| CN-110461887-A | Cured film is formed with composition, orientation material and phase difference material | NISSAN CHEMICAL CORP | 2019-11-15 | — | — | CN | disclosed |
| CN-110003214-A | Substituted pyrazolo [1,5-a] pyrimidine compound as TRK kinase inhibitor | 阵列生物制药公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-109476926-A | Polymer composition | 日产化学株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-106008523-B | Substituted pyrazolo [1,5-a] pyrimidine compound as TRK kinase inhibitor | 阵列生物制药公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-109154685-A | Both alignment layers form composition | 日产化学株式会社 | 2019-01-04 | — | — | CN | disclosed |
| US-5011995-A | Hydrogenation of N-Aliphatic Keimines Using A Complex Iridium Catalyst | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0419409-A2 | Iridium complexes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1991-03-27 | — | — | EP | disclosed |
| US-4996361-A | Catalytic hydrogenation of ketimine | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1991-02-26 | — | — | US | disclosed |
| US-4994615-A | Hydrogenation of prochiral N-arylketimines using iridium catalyst | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4990232-A | Photooxidation of N,N*-substituted thiourea | CIBA-GEIGY CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0307361-A2 | Process for the preparation of carbodiimides | CIBA-GEIGY AG (CH) | 1989-03-15 | — | — | EP | disclosed |
| EP-0301457-A2 | Process for the preparation of optically active secondary amines | CIBA-GEIGY AG (CH) | 1989-02-01 | — | — | EP | disclosed |
| EP-0302021-A2 | Process for the preparation of optically active secondary aryl amines | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1989-02-01 | — | — | EP | disclosed |
| EP-0256982-A2 | Method for the preparation of optically active secondary aryl amines | CIBA-GEIGY AG (CH) | 1988-02-24 | — | — | EP | disclosed |