⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127604 | 1.00 | — | — | |
| SCHEMBL1647946 | 0.74 | — | — | |
| SCHEMBL5439701 | 0.74 | — | — | |
| SCHEMBL345700 | 0.74 | — | — | |
| SCHEMBL10423010 | 0.71 | — | — | |
| SCHEMBL9752905 | 0.71 | — | — | |
| SCHEMBL1697256 | 0.70 | — | — | |
| SCHEMBL501854 | 0.70 | — | — | |
| SCHEMBL1478656 | 0.70 | — | — | |
| SCHEMBL1187300 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2305 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570590-B2 | Method for manufacturing 2-Chloro-1, 1-difluoroethane (HCFC-142), 1,1,2-trifluoroethane (HFC-143), and (E)-1,2-difluoroethylene (HFO-1132(E)) and/or (Z)-1,2-difluoroethylene (HFO-1132(Z)) | DAIKIN INDUSTRIES, LTD. (JP) | 2026-03-10 | — | — | US | claimed |
| US-20260062365-A1 | METHOD FOR PRODUCING trans-1,2-DIFLUOROETHYLENE (HFO-1132E) | SOLSTICE ADVANCED MATERIALS US, INC. | 2026-03-05 | — | — | US | claimed |
| EP-4688710-A1 | METHOD FOR PRODUCING TRANS-1,2-DIFLUOROETHYLENE (HFO-1132E) | HONEYWELL INTERNATIONAL INC. (US) | 2026-02-11 | — | — | EP | claimed |
| WO-2025137535-A1 | CATALYST CONDITIONING AND REACTANT DILUTION METHODS IN PROCESSES FOR PRODUCING TRANS-1,2-DIFLUOROETHYLENE (HFO-1132E) | HONEYWELL INTERNATIONAL INC. (US) | 2025-06-26 | — | — | WO | claimed |
| US-20250206689-A1 | CATALYST CONDITIONING AND REACTANT DILUTION METHODS IN PROCESSES FOR PRODUCING trans-1,2-DIFLUOROETHYLENE (HFO-1132E) | SOLSTICE ADVANCED MATERIALS US, INC. | 2025-06-26 | — | — | US | claimed |
| CN-119977813-A | Preparation method of difluoroethylamine | 宁夏滨河泽瑞新材料科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119390530-B | Borane-participated 2, 2-difluoroethanol preparation reaction | 山东东岳绿冷科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119219888-B | Polyurethane super-hydrophobic foam composite material for packaging and preparation method thereof | 山东一诺威新材料有限公司 | 2025-04-15 | — | — | CN | claimed |
| WO-2025072109-A2 | PROCESS OF COPRODUCING HFO-E/Z-1132 AND COMPOSITIONS THEREOF | THE CHEMOURS COMPANY FC, LLC (US) | 2025-04-03 | — | — | WO | claimed |
| CN-116003252-B | Preparation method and reaction device of difluoroethyl acetate | 济南正光化工科技开发有限公司 | 2025-03-25 | — | — | CN | claimed |
| EP-0309345-A1 | Surface modified polymeric material article with an improved hemocompatibility an lower thrombogenicity, and method for making the same | INSTITUT DE RECHERCHE APPLIQUEE SUR LES POLYMERES (I.R.A.P.) (FR) | 1989-03-29 | — | — | EP | claimed |
| EP-0306861-A2 | Stabilisation of chlorofluoroalkanes | Kali-Chemie Aktiengesellschaft (DE) | 1989-03-15 | — | — | EP | claimed |
| EP-0167450-B1 | USE OF STABLE MIXTURES OF CHLOROFLUORINATED HYDROCARBONS AND SOLVENTS AS HEAT-TRANSFER COMPOSITIONS FOR ABSORPTION HEAT-PUMP AND HEAT-TRANSFER COMPOSITIONS | GAZ DE FRANCE (FR) | 1989-02-08 | — | — | EP | claimed |
| EP-0283261-A2 | Herbicidal substituted cyclic diones | ZENECA LIMITED (GB) | 1988-09-21 | — | — | EP | claimed |
| US-4766258-A | REACTING A HYDROCARBON HALIDE AND HYDROGEN FLUORIDE USING A TIN COMPOUND/OXYGEN-OR NITROGEN-CONTAINING COMPOUND/HYDROFLUORIC ACID REACTION PRODUCT; CATALYST SELECTIVITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-08-23 | — | — | US | claimed |
| US-4710312-A | ZINC DIALKYLDITHIOPHOSPHATE STABILIZER | GAZ DE FRANCE (FR) | 1987-12-01 | — | — | US | claimed |
| US-4612133-A | Stable mixtures of chlorofluorocarbons and solvents and their use as heat transfer fluids | ATOCHEM (FR) | 1986-09-16 | — | — | US | claimed |
| US-4495776-A | MIXTURE OF COMPONENTS WITH DIFFERENT BOILING POINTS | VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY EXPERMINETALNO KONSTRUKTORSKY INSTITUT ELEKTROBYTOVYKY MACHIN I PRIBOROV (SU) | 1985-01-29 | — | — | US | claimed |
| EP-0098341-A1 | Anhydrous phase separation for recovering hydrogen fluoride from a fluorination reaction | PENNWALT CORPORATION (US) | 1984-01-18 | — | — | EP | claimed |
| US-4308352-A | Process of extruding polysulfone foam | PACKAGING INDUSTRIES GROUP, INC. (US) | 1981-12-29 | — | — | US | claimed |