Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 4/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14816832 | 0.93 | PRMT1 (0.47) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14816857 | 0.89 | PRMT1 (0.45) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14816838 | 0.87 | PRMT1 (0.53) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854502 | 0.86 | PRMT1 (0.46) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14816831 | 0.82 | PRMT1 (0.48) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| Acetic Acid SCHEMBL14784386 | 0.80 | PRMT1 (0.48) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14816854 | 0.80 | PRMT1 (0.44) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| Acetic Acid SCHEMBL14842869 | 0.80 | PRMT1 (0.46) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854584 | 0.79 | PRMT3 (0.41) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| Acetic Acid SCHEMBL14786469 | 0.79 | PRMT1 (0.46) | PRMT1PRMT3EHMT2PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013040528-A1 | ANTIMICROBIAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2013-03-21 | — | — | WO | disclosed |