SCHEMBL1478673

SCHEMBL1478673

O=C(O)C1=CCCCCC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 4/20 0.57
HDAC4 P56524 2/20 0.57
HDAC8 Q9BY41 2/20 0.57
HDAC6 Q9UBN7 2/20 0.57
HDAC1 Q13547 3/20 0.48
HDAC3 O15379 2/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48
CTSK P43235 1/20 0.46
TSHR P16473 3/20 0.43
SLC6A1 P30531 1/20 0.43
SLC6A13 Q9NSD5 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRR1 P24046 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL518451 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL19359633 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL30490816 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL518453 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL1628262 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL6885892 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL20184157 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL11169389 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL11169395 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL28247735 1.00 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2699606-B1 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORP (JP) 2016-09-28 EP claimed
WO-2016119848-A1 METHOD FOR THE PREPARATION OF CYCLOALIPHATIC EPOXY RESINS HENKEL AG & CO. KGAA (DE) 2016-08-04 WO claimed
US-9040259-B2 Production of polyketides and other natural products BUCK INSTITUTE FOR RESEARCH ON AGING (US) 2015-05-26 US claimed
EP-2483317-B1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2014-02-26 EP claimed
EP-2699606-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP Bridgestone Corporation (JP) 2014-02-26 EP claimed
US-20140018500-A1 Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group BRIDGESTONE CORPORATION (JP) 2014-01-16 US claimed
WO-2012135451-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-10-04 WO claimed
EP-2483317-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-08-08 EP claimed
US-20120184677-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2012-07-19 US claimed
US-20110165633-A1 Production of Polyketides and Other Natural Products BUCK INSTITUTE FOR RESEARCH ON AGING 2011-07-07 US claimed
EP-1589031-B1 Production of polyketides and other natural products BIOTICA TECH LTD (GB) 2007-08-15 EP claimed
JP-2007516982-A 2007-06-28 JP claimed
CN-1901971-A Cyclopropane compounds and pharmaceutical use thereof JAPAN TOBACCO INC (JP) 2007-01-24 CN claimed
EP-1694410-A2 CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF Japan Tobacco, Inc. (JP) 2006-08-30 EP claimed
EP-1655372-A2 Production of polyketides and other natural products Biotica Technology Limited (GB) 2006-05-10 EP claimed
US-20050272132-A1 Production of polyketides and other natural products BIOTICA TECHNOLOGY LIMITED (GB) 2005-12-08 US claimed
EP-1589031-A2 Production of polyketides and other natural products Biotica Technology Limited (GB) 2005-10-26 EP claimed
WO-2005058884-A2 CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2005-06-30 WO claimed
EP-1521828-A2 PRODUCTION OF POLYKETIDES Biotica Technology Limited (GB) 2005-04-13 EP claimed
WO-2004007709-A2 PRODUCTION OF POLYKETIDES BIOTICA TECHNOLOGY LIMITED (GB) 2004-01-22 WO claimed