Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.42 |
| ▸ | KDR | P35968 | 15/20 | 0.42 |
| ▸ | MST1R | Q04912 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15808458 | 0.89 | MET (0.41) | METKDRMST1R | |
| SCHEMBL15808456 | 0.89 | MET (0.41) | METKDRMST1R | |
| SCHEMBL1479209 | 0.87 | MET (0.48) | METKDRMST1R | |
| SCHEMBL1479000 | 0.86 | MET (0.53) | METKDRMST1R | |
| SCHEMBL1478646 | 0.85 | MET (0.47) | METKDRMST1R | |
| SCHEMBL106737 | 0.85 | MET (0.45) | METKDRMST1R | |
| SCHEMBL1481551 | 0.85 | PDGFRA (0.49) | METKDRMST1R | |
| SCHEMBL1478413 | 0.85 | MET (0.56) | METKDRMST1R | |
| SCHEMBL106462 | 0.83 | MET (0.42) | METKDRMST1R | |
| SCHEMBL1674666 | 0.83 | MST1R (0.43) | METKDRMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759522-B2 | Inhibitors of protein tyrosine kinase activity | METHYLGENE INC. (CA) | 2014-06-24 | — | — | US | disclosed |
| US-20110077240-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077240-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | ABL1, ERBB2, TYRO3 | MET 111/4885KDR 8/4885MST1R 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.