Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.33 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.33 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788171 | 0.95 | ALDH1A1 (0.52) | ALDH1A1MEN1HPGDRAB9AKMT2A | |
| 1,3,5-Trimethoxybenzene SCHEMBL31747519 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MEN1HPGDKMT2ACYP1A1 | |
| 1,3,5-Trimethoxybenzene SCHEMBL31747507 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MEN1HPGDKMT2ACYP1A1 | |
| SCHEMBL202288 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MEN1HPGDRAB9AKMT2A | |
| 1,3,5-Trimethoxybenzene SCHEMBL31747526 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MEN1HPGDKMT2ACYP1A1 | |
| SCHEMBL3966378 | 0.78 | ALDH1A1 (0.65) | ALDH1A1MEN1HPGDRAB9AKMT2A | |
| SCHEMBL2999328 | 0.78 | ALDH1A1 (0.65) | ALDH1A1MEN1HPGDRAB9AKMT2A | |
| SCHEMBL13948171 | 0.77 | — | — | |
| SCHEMBL29868308 | 0.77 | — | — | |
| SCHEMBL30252964 | 0.75 | ALDH1A1 (0.33) | ALDH1A1MEN1HPGDRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072457-A1 | PYRAZOLYL QUINAZOLINE KINASE INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072457-A1 | PYRAZOLYL QUINAZOLINE KINASE INHIBITORS | MAP3K5, MAP3K1, MAP4K2 | ALDH1A1 3640/4885MEN1 1371/4885HPGD 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.