Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | OXTR | P30559 | 3/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478740 | 0.83 | — | — | |
| SCHEMBL11897856 | 0.82 | KDM4E (0.46) | MAPK1KDM4EL3MBTL1CYP1A2TDP1 | |
| SCHEMBL15484386 | 0.76 | KDM4E (0.30) | KDM4EL3MBTL1CYP1A2TDP1ALDH1A1 | |
| SCHEMBL1479280 | 0.71 | CYP1A2 (0.50) | MAPK1KDM4ECYP1A2ALDH1A1LMNA | |
| SCHEMBL10472754 | 0.70 | MAPK1 (0.56) | MAPK1KDM4EL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL11897885 | 0.67 | TDP1 (0.34) | KDM4ETDP1ALDH1A1MAPTALOX15 | |
| SCHEMBL1479026 | 0.67 | MAPT (0.44) | KDM4EL3MBTL1CYP1A2TDP1ALDH1A1 | |
| SCHEMBL150122 | 0.66 | HDAC6 (0.37) | KDM4ECYP1A2MEN1CYP3A4MAPT | |
| SCHEMBL17673994 | 0.66 | CYP2C19 (0.49) | KDM4ECYP1A2ALDH1A1MEN1LMNA | |
| SCHEMBL27665226 | 0.65 | ALDH1A1 (0.46) | MAPK1KDM4ECYP1A2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | claimed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | claimed |
| US-9403919-B2 | Polymers functionalized with a carboxylic or thiocarboxylic ester containing a silylated amino group | BRIDGESTONE CORPORATION (JP) | 2016-08-02 | — | — | US | disclosed |
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2483317-B1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2014-02-26 | — | — | EP | disclosed |
| US-20140018500-A1 | Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group | BRIDGESTONE CORPORATION (JP) | 2014-01-16 | — | — | US | disclosed |
| US-20120184677-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2012-07-19 | — | — | US | disclosed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |