Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14786385 | 0.91 | CYP4F2 (0.42) | CYP4F2CYP4A11HTTMEN1KMT2A | |
| SCHEMBL2139741 | 0.80 | CYP4F2 (0.59) | CYP4F2CYP4A11HTTMEN1KMT2A | |
| SCHEMBL30724478 | 0.80 | CYP4F2 (0.59) | CYP4F2CYP4A11HTTMEN1KMT2A | |
| SCHEMBL1438717 | 0.76 | CYP4F2 (0.41) | CYP4F2CYP4A11HTTMEN1KMT2A | |
| SCHEMBL5857185 | 0.76 | CYP4F2 (0.35) | CYP4F2CYP4A11HTTMEN1KMT2A | |
| SCHEMBL17891871 | 0.74 | CYP4F2 (0.54) | CYP4F2CYP4A11HTTMEN1KMT2A | |
| SCHEMBL16668890 | 0.71 | DGKA (0.44) | KMT2AALDH1A1CYP1A2TSHR | |
| SCHEMBL6829991 | 0.68 | MEN1 (0.56) | CYP4F2CYP4A11HTTMEN1KMT2A | |
| SCHEMBL7509043 | 0.68 | MEN1 (0.56) | CYP4F2CYP4A11HTTMEN1KMT2A | |
| SCHEMBL7505989 | 0.68 | MEN1 (0.56) | CYP4F2CYP4A11HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013038153-A1 | 18F-LABELLED BARBITURATE COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2013-03-21 | — | — | WO | disclosed |