Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.59 |
| ▸ | CA1 | P00915 | 6/20 | 0.59 |
| ▸ | CA2 | P00918 | 6/20 | 0.59 |
| ▸ | CA7 | P43166 | 6/20 | 0.59 |
| ▸ | CA9 | Q16790 | 6/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343211 | 0.92 | CA1 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2281149 | 0.90 | CA12 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10787290 | 0.84 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30864246 | 0.81 | HPGD (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11865229 | 0.81 | HPGD (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11107585 | 0.81 | ESR1 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL742830 | 0.81 | SMN1; SMN2 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL439997 | 0.80 | CA12 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10788591 | 0.80 | EGFR (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19024747 | 0.79 | CA12 (0.54) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1378348-B1 | Thermosensitive lithographic printing plate | FUJIFILM CORP (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-7914787-B2 | Provide inter alia a bi-specific antibody or antibody fragment having one arm that specifically binds a targeted tissue and one other arm that specifically binds a targetable conjugate that can be modified for use in a wide variety of diagnostic and therapeutic applications | IMMUNOMEDICS, INC. (US) | 2011-03-29 | — | — | US | disclosed |