SCHEMBL742830

SCHEMBL742830

COc1ccc(O)c(C(=O)Oc2ccc(O)c(C(=O)O)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.51
HPGD P15428 5/20 0.51
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
KMT2A Q03164 4/20 0.51
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 3/20 0.51
MEN1 O00255 3/20 0.51
LMNA P02545 3/20 0.51
HSD17B10 Q99714 3/20 0.51
TP53 P04637 2/20 0.51
MAPT P10636 2/20 0.51
ALOX12 P18054 2/20 0.51
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
ALOX5 P09917 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128781 0.90 CA1 (0.61) SMN1; SMN2HPGDNPC1RAB9AKMT2A
SCHEMBL29431885 0.90 CA1 (0.61) SMN1; SMN2HPGDNPC1RAB9AKMT2A
SCHEMBL343211 0.89 CA1 (0.67) HPGDNPC1KMT2AKDM4EALDH1A1
SCHEMBL865333 0.88 SMN1; SMN2 (0.59) SMN1; SMN2HPGDNPC1RAB9AKMT2A
Methyl 2-Hydroxy-5-Methoxybenzoate SCHEMBL29709382 0.81 CA1 (0.72) SMN1; SMN2HPGDNPC1RAB9AKMT2A
Methyl 2-Hydroxy-5-Methoxybenzoate SCHEMBL643758 0.81 CA1 (0.72) SMN1; SMN2HPGDNPC1RAB9AKMT2A
SCHEMBL1478993 0.81 CA12 (0.59) SMN1; SMN2HPGDNPC1RAB9AALDH1A1
SCHEMBL344841 0.80 KDM4E (0.64) HPGDKMT2AKDM4EALDH1A1MEN1
SCHEMBL31364552 0.80 KDM4E (0.64) HPGDKMT2AKDM4EALDH1A1MEN1
SCHEMBL7030719 0.79 KMT2A (0.60) SMN1; SMN2HPGDNPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112654642-B Glycan analysis of proteins and cells MUSC研究发展基金会 2023-04-28 CN disclosed
US-20210208156-A1 GLYCAN ANALYSIS OF PROTEINS AND CELLS VAN ANDEL RESEARCH INSTITUTE 2021-07-08 US disclosed
EP-3802624-A1 GLYCAN ANALYSIS OF PROTEINS AND CELLS Musc Foundation for Research Development (US) 2021-04-14 EP disclosed
CN-112654642-A Glycan analysis of proteins and cells MUSC研究发展基金会 2021-04-13 CN disclosed
US-20200255518-A1 ANTIBODIES WITH ENHANCED ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY ACTIVITY, METHODS OF THEIR PRODUCTION AND USE LFB USA, INC. (US) 2020-08-13 US disclosed
EP-2388273-B1 Antibodies with enhanced antibody-dependent cellular cytoxicity activity, methods of their production and use LFB USA INC (US) 2017-07-05 EP disclosed
US-20170002095-A1 CANCER SPECIFIC GLYCANS AND USE THEREOF GLYKOS FINLAND OY (FI) 2017-01-05 US disclosed
US-9410126-B2 Carbohydrate profile compositions from human cells and methods for analysis and modification thereof GLYKOS FINLAND OY (FI) 2016-08-09 US disclosed
WO-2016036705-A1 GLYCAN PANELS AS SPECIFIC TUMOR TISSUE BIOMARKERS MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2016-03-10 WO disclosed
US-20150140576-A1 CANCER SPECIFIC GLYCANS AND USE THEREOF GLYKOS FINLAND OY (FI) 2015-05-21 US disclosed
US-20080118501-A1 Antibodies with enhanced antibody-dependent cellular cytotoxicity activity, methods of their production and use GTC BIOTHERAPEUTICS, INC. (US) 2008-05-22 US disclosed
EP-1913385-A2 TISSUE CARBOHYDRATE COMPOSITIONS AND ANALYSIS THEREOF Glykos Finland Oy (FI) 2008-04-23 EP disclosed
EP-1910838-A2 CANCER SPECIFIC GLYCANS AND USE THEREOF Glykos Finland Oy (FI) 2008-04-16 EP disclosed
EP-1904532-A2 NOVEL CARBOHYDRATE PROFILE COMPOSITIONS FROM HUMAN CELLS AND METHODS FOR ANALYSIS AND MODIFICATION THEREOF SUOMEN PUNAINEN RISTI VERIPALVELU (FI) 2008-04-02 EP disclosed
WO-2007054622-A1 NOVEL CARBOHYDRATE PROFILE COMPOSITIONS FROM HUMAN CELLS AND METHODS FOR ANALYSIS AND MODIFICATION THEREOF SUOMEN PUNAINEN RISTI, VERIPALVELU (FI) 2007-05-18 WO disclosed
WO-2007054621-A1 TISSUE CARBOHYDRATE COMPOSITIONS AND ANALYSIS THEREOF GLYKOS FINLAND OY (FI) 2007-05-18 WO disclosed
WO-2007048077-A2 ANTIBODIES WITH ENHANCED ANTIBODY-DEPENDENT CELLULAR CYTOXICITY ACTIVITY, METHODS OF THEIR PRODUCTION AND USE GTC BIOTHERAPEUTICS, INC. (US) 2007-04-26 WO disclosed
WO-2007012695-A2 TISSUE CARBOHYDRATE COMPOSITIONS AND ANALYSIS THEREOF GLYKOS FINLAND OY (FI) 2007-02-01 WO disclosed
WO-2007010089-A2 CANCER SPECIFIC GLYCANS AND USE THEREOF GLYKOS FINLAND OY (FI) 2007-01-25 WO disclosed
WO-2007006870-A2 NOVEL CARBOHYDRATE PROFILE COMPOSITIONS FROM HUMAN CELLS AND METHODS FOR ANALYSIS AND MODIFICATION THEREOF SUOMEN PUNAINEN RISTI, VERIPALVELU (FI) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150140576-A1 CANCER SPECIFIC GLYCANS AND USE THEREOF SIGLEC7, FUT5, SIGLEC9 SMN1; SMN2 4793/4885HPGD 2666/4885NPC1 1788/4885
US-20170002095-A1 CANCER SPECIFIC GLYCANS AND USE THEREOF SIGLEC7, FUT5, SIGLEC9 SMN1; SMN2 4793/4885HPGD 2666/4885NPC1 1788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.