Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.63 |
| ▸ | TUBB | P07437 | 1/20 | 0.63 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.63 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.63 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.63 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.63 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.63 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.63 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.63 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.63 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.63 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.63 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.63 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.63 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.63 |
| ▸ | FLT1 | P17948 | 8/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | RAF1 | P04049 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19255985 | 0.91 | FLT1 (0.62) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14777505 | 0.89 | FLT1 (0.77) | EGFRFLT1FGFR1KDRRAF1 | |
| SCHEMBL14777006 | 0.88 | EGFR (0.62) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14776758 | 0.88 | EGFR (0.69) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19256223 | 0.85 | FLT1 (0.58) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14776903 | 0.85 | FLT1 (0.58) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14777324 | 0.84 | FLT1 (0.59) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14790820 | 0.84 | FLT1 (0.54) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14777200 | 0.84 | FLT1 (0.54) | EGFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14777680 | 0.83 | FLT1 (0.53) | EGFRTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062066-B2 | Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases and pharmaceutical composition containing same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-06-23 | — | — | US | disclosed |
| US-20130072482-A1 | ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | PHAROSBIOMED CO., LTD. (KR) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072482-A1 | ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | LCK, SRC, MAP3K1 | EGFR 682/4885TUBB4A 2832/4885TUBB 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.