SCHEMBL14791122

SCHEMBL14791122

Cc1nc2c(C)c(C)c(C)c(=O)n2c(C)c1C

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.31
KDM4E B2RXH2 3/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 2/20 0.30
MAPT P10636 1/20 0.30
JAK2 O60674 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14791121 0.92 ALDH1A1 (0.30) ALDH1A1KDM4EHPGDMAPTJAK2
SCHEMBL14791114 0.75 PDE5A (0.33)
SCHEMBL14341721 0.72 KDM4E (0.32) ALDH1A1KDM4ESMN1; SMN2
SCHEMBL14341718 0.67 KDM4E (0.33) ALDH1A1KDM4EPKMSMN1; SMN2LMNA
SCHEMBL8279214 0.65
SCHEMBL12149793 0.64 KDM4C (0.35) ALDH1A1KDM4ESMN1; SMN2HPGDMAPT
SCHEMBL14341745 0.64 KDM4E (0.32) ALDH1A1KDM4ESMN1; SMN2
SCHEMBL26006992 0.62 ALDH1A1 (0.31) ALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL14341758 0.62 ADORA2A (0.32) ALDH1A1KDM4ESMN1; SMN2LMNA
SCHEMBL19626314 0.62 ALDH1A1 (0.34) ALDH1A1KDM4EPKMSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382481-B2 Polarizing film, display device and production process thereof FUJIFILM CORPORATION (JP) 2016-07-05 US disclosed
US-20130120676-A1 STEREO IMAGE PRINT AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2013-05-16 US disclosed
US-20130070899-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2013-03-21 US disclosed