Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799659 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL15438820 | 0.90 | HTT (0.38) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL15438818 | 0.90 | HTT (0.38) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL15440029 | 0.80 | HTT (0.48) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL15440027 | 0.80 | HTT (0.48) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL15440257 | 0.75 | HTT (0.39) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL11873794 | 0.75 | GAA (0.41) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL15438969 | 0.75 | SMN1; SMN2 (0.33) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL11873789 | 0.75 | GAA (0.41) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL15438971 | 0.75 | SMN1; SMN2 (0.33) | SMN1; SMN2NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |