Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15438820 | 1.00 | HTT (0.38) | HTTNPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL14799659 | 0.90 | SMN1; SMN2 (0.32) | NPC1SMN1; SMN2RAB9AMAPTLMNA | |
| SCHEMBL14799398 | 0.90 | SMN1; SMN2 (0.32) | NPC1SMN1; SMN2RAB9AMAPTLMNA | |
| SCHEMBL15440029 | 0.88 | HTT (0.48) | HTTNPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL15440027 | 0.88 | HTT (0.48) | HTTNPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL15439962 | 0.83 | HTT (0.34) | HTTNPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL15440259 | 0.83 | HTT (0.39) | HTTNPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL15439960 | 0.83 | HTT (0.34) | HTTNPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL15440257 | 0.83 | HTT (0.39) | HTTNPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL11873789 | 0.76 | GAA (0.41) | HTTNPC1SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |