Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 7/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440296 | 0.84 | G6PC1 (0.47) | G6PC1SLC18A3CA12CA9NPC1 | |
| SCHEMBL15440298 | 0.84 | G6PC1 (0.47) | G6PC1SLC18A3CA12CA9NPC1 | |
| SCHEMBL15440307 | 0.81 | G6PC1 (0.44) | G6PC1CA12CA9NPC1RAB9A | |
| SCHEMBL15440305 | 0.81 | G6PC1 (0.44) | G6PC1CA12CA9NPC1RAB9A | |
| SCHEMBL16492405 | 0.80 | G6PC1 (0.36) | G6PC1SLC18A3CA12CA9NPC1 | |
| SCHEMBL15438775 | 0.71 | NPC1 (0.44) | G6PC1SLC18A3CA12CA9NPC1 | |
| SCHEMBL15438772 | 0.71 | NPC1 (0.44) | G6PC1SLC18A3CA12CA9NPC1 | |
| SCHEMBL14799538 | 0.70 | G6PC1 (0.69) | G6PC1NOS2CA12CA9NPC1 | |
| SCHEMBL14799539 | 0.70 | G6PC1 (0.69) | G6PC1NOS2CA12CA9NPC1 | |
| SCHEMBL15440173 | 0.69 | NPC1 (0.38) | G6PC1CA12CA9NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |