SCHEMBL14799456

SCHEMBL14799456

CN(C)N=C1C=CC=CC1=NN(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
NSD2 O96028 1/20 0.38
DNMT1 P26358 1/20 0.38
DEPTOR Q8TB45 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15439587 0.82 IDO1 (0.31) IDO1TDO2NSD2DNMT1
SCHEMBL14800156 0.73 IDO1 (0.32) IDO1TDO2NSD2DNMT1
SCHEMBL16492433 0.69 IDO1 (0.33) IDO1TDO2NSD2DNMT1
SCHEMBL14799501 0.67 DEPTOR (0.38) DEPTOR
SCHEMBL19679968 0.62 IDO1 (0.44) IDO1TDO2NSD2DNMT1
SCHEMBL18071732 0.57 DEPTOR (0.31) DEPTOR
SCHEMBL15440549 0.57 MIF (0.44) DEPTOR
SCHEMBL15627385 0.56 IDO1 (0.38) IDO1TDO2NSD2DNMT1
SCHEMBL336846 0.55
SCHEMBL14799473 0.54 DEPTOR (0.38) DEPTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed