SCHEMBL14799467

SCHEMBL14799467

C[Si](C)(C)N(N=C1C=CC(=NN(c2ccccc2)[Si](C)(C)C)C=C1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15439661 0.91 ALDH1A1 (0.33) ALDH1A1ALOX15MEN1HTTKMT2A
SCHEMBL14799510 0.80 ALDH1A1 (0.30) ALDH1A1ALOX15
SCHEMBL14799630 0.78 ALDH1A1 (0.31) ALDH1A1ALOX15MEN1HTTKMT2A
SCHEMBL30995126 0.76 ALDH1A1 (0.36) ALDH1A1ALOX15MEN1HTTKMT2A
SCHEMBL14800155 0.75 CHRNB4 (0.32)
SCHEMBL14800154 0.75 CHRNB4 (0.32)
SCHEMBL14799385 0.75 DEPTOR (0.39) ALDH1A1
SCHEMBL14799824 0.75 SMN1; SMN2 (0.31)
SCHEMBL14799455 0.73 POLB (0.30)
SCHEMBL15440404 0.73 PTPN1 (0.31) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed