Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799521 | 1.00 | MAPT (0.57) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15439453 | 0.88 | CYP2A6 (0.52) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15272182 | 0.88 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15439454 | 0.88 | CYP2A6 (0.52) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7642232 | 0.88 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16609589 | 0.88 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25989380 | 0.88 | ALDH1A1 (0.61) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15272180 | 0.88 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22203792 | 0.88 | ALDH1A1 (0.61) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10673356 | 0.87 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |