Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799589 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL15440159 | 0.92 | ALDH1A1 (0.40) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL15440156 | 0.92 | ALDH1A1 (0.40) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL14799726 | 0.89 | ATM (0.35) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL14799728 | 0.89 | ATM (0.35) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL14799570 | 0.89 | ALDH1A1 (0.37) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL14799573 | 0.89 | ALDH1A1 (0.37) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL15439004 | 0.88 | NR4A2 (0.45) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL15439006 | 0.88 | NR4A2 (0.45) | ALDH1A1MAPK1KMT2AMEN1GAA | |
| SCHEMBL14799443 | 0.84 | MEN1 (0.36) | ALDH1A1MAPK1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |