SCHEMBL14799602

SCHEMBL14799602

C[Si](C)(C)N(Cc1ccccc1)N=C(CCC(=NN(Cc1ccccc1)[Si](C)(C)C)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.47
GAA P10253 3/20 0.40
ATM Q13315 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 1/20 0.38
AOC3 Q16853 1/20 0.36
CTSL P07711 1/20 0.36
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14799601 1.00 G6PC1 (0.47) G6PC1GAAATMNPC1RAB9A
SCHEMBL14799480 0.94 G6PC1 (0.45) G6PC1GAAATMNPC1RAB9A
SCHEMBL14799479 0.94 G6PC1 (0.45) G6PC1GAAATMNPC1RAB9A
SCHEMBL14798836 0.93 G6PC1 (0.45) G6PC1GAAATMNPC1RAB9A
SCHEMBL14798837 0.93 G6PC1 (0.45) G6PC1GAAATMNPC1RAB9A
SCHEMBL15439405 0.91 NR4A2 (0.44) G6PC1GAANPC1RAB9AALDH1A1
SCHEMBL15440268 0.91 G6PC1 (0.44) G6PC1GAANPC1RAB9AALDH1A1
SCHEMBL15439406 0.91 NR4A2 (0.44) G6PC1GAANPC1RAB9AALDH1A1
SCHEMBL15440269 0.91 G6PC1 (0.44) G6PC1GAANPC1RAB9AALDH1A1
SCHEMBL15440538 0.86 TDP1 (0.48) G6PC1NPC1RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed