Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535664 | 0.97 | SCN5A (0.44) | SCN5ASCN9ASCN10A | |
| SCHEMBL4126064 | 0.90 | SCN5A (0.46) | SCN5ASCN9ASCN10A | |
| SCHEMBL14816076 | 0.86 | SCN5A (0.45) | SCN5ASCN9ASCN10A | |
| SCHEMBL27709035 | 0.84 | POLM (0.49) | — | |
| SCHEMBL14815784 | 0.84 | SCN5A (0.44) | SCN5ASCN9ASCN10A | |
| SCHEMBL29998258 | 0.84 | ATM (0.45) | — | |
| SCHEMBL17372982 | 0.83 | POLM (0.51) | — | |
| SCHEMBL9754189 | 0.82 | SCN5A (0.47) | SCN5ASCN9ASCN10A | |
| SCHEMBL21574518 | 0.82 | SCN5A (0.48) | SCN5ASCN9ASCN10A | |
| SCHEMBL13448904 | 0.79 | SCN5A (0.48) | SCN5ASCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586768-B1 | HYDROXY ACID ESTER OF PROPOFOL, PREPARATION METHOD AND MEDICAL USE | WEST CHINA HOSPITAL SICHUAN UNIV (CN) | 2018-06-27 | — | — | EP | disclosed |
| US-9272978-B2 | Hydroxy acid ester compound of substituted phenol, preparation method and medical use thereof | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2016-03-01 | — | — | US | disclosed |
| US-9243009-B2 | Phosphate ester compound of hydroxy acid substituted phenol ester, preparation method and medical use thereof | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2016-01-26 | — | — | US | disclosed |
| EP-2586785-B1 | PHOSPHORIC ACID ESTER COMPOUND OF HYDROXY ACID SUBSTITUTED PHENYL ESTER, SYNTHESIS METHOD AND MEDICAL USE THEREOF | WEST CHINA HOSPITAL SICHUAN UNIV (CN) | 2015-12-16 | — | — | EP | disclosed |
| EP-2586785-A1 | PHOSPHORIC ACID ESTER COMPOUND OF HYDROXY ACID SUBSTITUTED PHENYL ESTER, SYNTHESIS METHOD AND MEDICAL USE THEREOF | West China Hospital Sichuan University (CN) | 2013-05-01 | — | — | EP | disclosed |
| EP-2586768-A1 | HYDROXY ACID COMPOUND OF SUBSTITUTED PHENYL ESTER, PREPARATION METHOD AND MEDICAL USE THEREOF | West China Hospital Sichuan University (CN) | 2013-05-01 | — | — | EP | disclosed |
| US-20130085120-A1 | Phosphate Ester Compound of Hydroxy Acid Substituted Phenol Ester, Preparation Method and Medical Use Thereof | Yichang Humanwell Pharmaceutical Co., Ltd. (CN) | 2013-04-04 | — | — | US | disclosed |
| US-20130079405-A1 | Hydroxy Acid Ester Compound of Substituted Phenol, Preparation Method and Medical Use Thereof | WEST CHINA HOSPITAL SICHUAN UNIVERSITY (CN) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079405-A1 | Hydroxy Acid Ester Compound of Substituted Phenol, Preparation Method and Medical Use Thereof | CYP3A4, CYP2C19, CYP2A6 | SCN5A 2382/4885SCN9A 2366/4885SCN10A 2476/4885 |
| US-20130085120-A1 | Phosphate Ester Compound of Hydroxy Acid Substituted Phenol Ester, Preparation Method and Medical Use Thereof | HPD, PAH, CYP3A4 | SCN5A 1351/4885SCN9A 1248/4885SCN10A 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.